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WSES-BACS&TI

Acute Appendicitis
Yamashita H, Yuasa N, Takeuchi E, Goto Y, Miyake H, Miyata K, Kato H, Ito M. Diagnostic value of procalcitonin for acute complicated appendicitis. Nagoya J Med Sci. 2016 Feb;78(1):79-88.
Li Y, Zhang Z, Cheang I, Li X. Procalcitonin as an excellent differential marker between uncomplicated and complicated acute appendicitis in adult patients. Eur J Trauma Emerg Surg. 2020 Aug;46(4):853-858. doi: 10.1007/s00068-019-01116-2. Epub 2019 May 13.
Dale L. The Use of Procalcitonin in the Diagnosis of Acute Appendicitis: A Systematic Review. Cureus. 2022 Oct 14;14(10):e30292. doi: 10.7759/cureus.30292.
Yu CW, Juan LI, Wu MH, Shen CJ, Wu JY, Lee CC. Systematic review and meta-analysis of the diagnostic accuracy of procalcitonin, C-reactive protein and white blood cell count for suspected acute appendicitis. Br J Surg. 2013 Feb;100(3):322-9. doi: 10.1002/bjs.9008. Epub 2012 Nov 30.
Haghi AR, Kasraianfard A, Monsef A, Kazemi AS, Rahimi S, Javadi SMR. The diagnostic values of procalcitonin and interleukin 6 in acute appendicitis. Turk J Surg. 2018 Nov 20;35(1):1-3. doi: 10.5152/turkjsurg.2018.4113. Epub ahead of print.
Motie MR, Soleimani A, Soltani A, Hashemy SI. Serum Procalcitonin and Lactoferrin in Detection of Acute Appendicitis; a Diagnostic Accuracy Study. Emerg (Tehran). 2018;6(1):e51. Epub 2018 Aug 25.
Cui W, Liu H, Ni H, Qin X, Zhu L. Diagnostic accuracy of procalcitonin for overall and complicated acute appendicitis in children: a meta-analysis. Ital J Pediatr. 2019 Jul 9;45(1):78. doi: 10.1186/s13052-019-0673-3.
Kaya B, Sana B, Eris C, Karabulut K, Bat O, Kutanis R. The diagnostic value of D-dimer, procalcitonin and CRP in acute appendicitis. Int J Med Sci. 2012;9(10):909-15. doi: 10.7150/ijms.4733. Epub 2012 Nov 13.
Acharya A, Markar SR, Ni M, Hanna GB. Biomarkers of acute appendicitis: systematic review and cost-benefit trade-off analysis. Surg Endosc. 2017 Mar;31(3):1022-1031. doi: 10.1007/s00464-016-5109-1. Epub 2016 Aug 5.
Pérez-Soto RH, Ponce de León-Ballesteros G, Álvarez-Bautista F, Trolle-Silva AM, Medina-Franco H. Thrombocytosis and Hyponatremia as Predictors of Complicated Acute Appendicitis: Predictors of Appendicitis. J Surg Res. 2021 May;261:369-375. doi: 10.1016/j.jss.2020.12.050. Epub 2021 Jan 22.
Vaziri M, Ehsanipour F, Pazouki A, Tamannaie Z, Taghavi R, Pishgahroudsari M, Jesmi F, Chaichian S. Evaluation of procalcitonin as a biomarker of diagnosis, severity and postoperative complications in adult patients with acute appendicitis. Med J Islam Repub Iran. 2014 Jul 7;28:50.
Abbas MH, Choudhry MN, Hamza N, Ali B, Amin AA, Ammori BJ. Admission levels of serum amyloid a and procalcitonin are more predictive of the diagnosis of acute appendicitis compared with C-reactive protein. Surg Laparosc Endosc Percutan Tech. 2014 Dec;24(6):488-94. doi: 10.1097/SLE.0000000000000067.
Destek S, Gül VO, MenteÅŸ MÖ, Çiçek AF. Diagnostic efficacy of serum procalcitonin, IL-6, IL-2, and D-dimer levels in an experimental acute appendicitis model. Turk J Gastroenterol. 2019 Jul;30(7):641-647. doi: 10.5152/tjg.2019.18534.
Kisacik B, Kalyoncu U, Erol MF, Karadag O, Yildiz M, Akdogan A, Kaptanoglu B, Hayran M, Ureten K, Ertenli I, Kiraz S, Calguneri M. Accurate diagnosis of acute abdomen in FMF and acute appendicitis patients: how can we use procalcitonin? Clin Rheumatol. 2007 Dec;26(12):2059-2062. doi: 10.1007/s10067-007-0617-y. Epub 2007 Apr 6.
Gavela T, Cabeza B, Serrano A, Casado-Flores J. C-reactive protein and procalcitonin are predictors of the severity of acute appendicitis in children. Pediatr Emerg Care. 2012 May;28(5):416-9. doi: 10.1097/PEC.0b013e318252d875.
Khan AN, Sawan A, Likourezos A, Schnellinger M, Garcia E. The usefulness of procalcitonin in the diagnosis of appendicitis in children: a pilot study. Emerg Med Int. 2012;2012:317504. doi: 10.1155/2012/317504. Epub 2012 Dec 5.
Sand M, Trullen XV, Bechara FG, Pala XF, Sand D, Landgrafe G, Mann B. A prospective bicenter study investigating the diagnostic value of procalcitonin in patients with acute appendicitis. Eur Surg Res. 2009;43(3):291-7. doi: 10.1159/000232939. Epub 2009 Aug 7.
Assarsson J, Körner U, Lundholm K. Evaluation of procalcitonin as a marker to predict antibiotic response in adult patients with acute appendicitis: a prospective observational study. Surg Infect (Larchmt). 2014 Oct;15(5):601-5. doi: 10.1089/sur.2013.064. Epub 2014 May 27.
Díaz López MI, Crespo Álvarez E, Martínez Manzano Á, Urrechaga E, Orgaz Morales MT, González Morales M, Martín García E, de Guadiana-Romualdo LG. Usefulness of extended inflammatory parameters related to neutrophil activation reported by Sysmex XN-1000 hematology analyzer for predicting complicated acute appendicitis. Comparison with canonical inflammatory laboratory tests. Cir Esp (Engl Ed). 2024 Feb 9:S2173-5077(24)00039-5. doi: 10.1016/j.cireng.2023.11.022. Epub ahead of print.
Kang CB, Li XW, Hou SY, Chi XQ, Shan HF, Zhang QJ, Li XB, Zhang J, Liu TJ. Preoperatively predicting the pathological types of acute appendicitis using machine learning based on peripheral blood biomarkers and clinical features: a retrospective study. Ann Transl Med. 2021 May;9(10):835. doi: 10.21037/atm-20-7883.
Orellana-Henriquez J, Robalino-Rodriguez I, Sanchez-Alban H, Franco-Orellana J, Oleas R, Baquerizo-Burgos J, Patiño-Aquin M, Torres-Herrera C, Puga-Tejada M. Predictive biomarkers for complicated acute appendicitis: A prospective Ecuadorian study. Cir Cir. 2020;88(5):599-607. English. doi: 10.24875/CIRU.20000256.
Chandel V, Batt SH, Bhat MY, Kawoosa NU, Yousuf A, Zargar BR. Procalcitonin as the biomarker of inflammation in diagnosis of appendicitis in pediatric patients and prevention of unnecessary appendectomies. Indian J Surg. 2011 Apr;73(2):136-41. doi: 10.1007/s12262-010-0214-1. Epub 2010 Dec 1.
Yang J, Liu C, He Y, Cai Z. Laboratory Markers in the Prediction of Acute Perforated Appendicitis in Children. Emerg Med Int. 2019 Sep 19;2019:4608053. doi: 10.1155/2019/4608053.
Kafetzis DA, Velissariou IM, Nikolaides P, Sklavos M, Maktabi M, Spyridis G, Kafetzis DD, Androulakakis E. Procalcitonin as a predictor of severe appendicitis in children. Eur J Clin Microbiol Infect Dis. 2005 Jul;24(7):484-7. doi: 10.1007/s10096-005-1360-4.
Blab E, Kohlhuber U, Tillawi S, Schweitzer M, Stangl G, Ogris E, Rokitansky A. Advancements in the diagnosis of acute appendicitis in children and adolescents. Eur J Pediatr Surg. 2004 Dec;14(6):404-9. doi: 10.1055/s-2004-821152.
Jimbo T, Masumoto K, Takayasu H, Shinkai T, Urita Y, Uesugi T, Gotoh C, Ono K, Sasaki T. Outcome of early discharge protocol after appendectomy for pediatric acute appendicitis. Pediatr Int. 2017 Jul;59(7):803-806. doi: 10.1111/ped.13290.
Wu JY, Chen HC, Lee SH, Chan RC, Lee CC, Chang SS. Diagnostic role of procalcitonin in patients with suspected appendicitis. World J Surg. 2012 Aug;36(8):1744-9. doi: 10.1007/s00268-012-1579-z.
Domínguez-Comesaña E, Ballinas-Miranda JR. La procalcitonina como marcador de infección intraabdominal. Cir Cir. 2014;82(2):231-239.
Sikander B, Rosenberg J, Fonnes S. Individual biomarkers in the blood are not yet applicable in diagnosing complicated appendicitis: A scoping review. Am J Emerg Med. 2023 May;67:100-107. doi: 10.1016/j.ajem.2023.02.016. Epub 2023 Feb 18.
Xie F, Wang L, Chen L, Li S, Shen Q, Li X, Liu T, Chen Y, Wang D. Clinical Characteristics of Pediatric Patients With Septic Shock Caused by Acute Appendicitis: A Case Series. Pediatr Emerg Care. 2023 Jul 1;39(7):511-515. doi: 10.1097/PEC.0000000000002946. Epub 2023 Apr 22.
Zhang T, Cheng Y, Zhou Y, Zhang Z, Qi S, Pan Z. Diagnostic performance of type I hypersensitivity-specific markers combined with CRP and IL-6 in complicated acute appendicitis in pediatric patients. Int Immunopharmacol. 2023 Nov;124(Pt B):110977. doi: 10.1016/j.intimp.2023.110977. Epub 2023 Sep 27.
Hakkoymaz H, Nazik S, SeyithanoÄŸlu M, Güler Ö, Åžahin AR, Cengiz E, Yazar FM. The value of ischemia-modified albumin and oxidative stress markers in the diagnosis of acute appendicitis in adults. Am J Emerg Med. 2019 Nov;37(11):2097-2101. doi: 10.1016/j.ajem.2019.03.005. Epub 2019 Mar 7.
Sobczak J, Burzyńska M, Sikora A, Wysocka A, Karawani J, Sikora JP. Post-Traumatic Stress Response and Appendicitis in Children-Clinical Usefulness of Selected Biomarkers. Biomedicines. 2023 Jul 2;11(7):1880. doi: 10.3390/biomedicines11071880.
Toker Kurtmen B, Ekemen Keles Y, Tekindal MA, Koyluoglu G, Yilmaz Ciftdogan D. Differentiating abdominal pain due to COVID-19 associated multisystem inflammatory syndrome from children with acute appendicitis: a score system. Pediatr Surg Int. 2023 Mar 10;39(1):151. doi: 10.1007/s00383-023-05432-y.
Banerjee A, Ratan SK, Neogi S, Goswami B, Dixit R, Panda SS. Role of Ultrasonography and Inflammatory Markers in Predicting Complicated Appendicitis. J Indian Assoc Pediatr Surg. 2022 Jul-Aug;27(4):448-454. doi: 10.4103/jiaps.jiaps_140_21. Epub 2022 Jul 26.
Fawkner-Corbett D, Hayward G, Alkhmees M, Van Den Bruel A, Ordóñez-Mena JM, Holtman GA. Diagnostic accuracy of blood tests of inflammation in paediatric appendicitis: a systematic review and meta-analysis. BMJ Open. 2022 Nov 3;12(11):e056854. doi: 10.1136/bmjopen-2021-056854.
Kouame DB, Garrigue MA, Lardy H, Machet MC, Giraudeau B, Robert M. La procalcitonine peut-elle aider au diagnostic des appendicites de l'enfant? [Is procalcitonin able to help in pediatric appendicitis diagnosis?]. Ann Chir. 2005 Mar;130(3):169-74. French. doi: 10.1016/j.anchir.2004.12.004. Epub 2005 Jan 7.
Anielski R, Kuśnierz-Cabala B, Szafraniec K. An evaluation of the utility of additional tests in the preoperative diagnostics of acute appendicitis. Langenbecks Arch Surg. 2010 Nov;395(8):1061-8. doi: 10.1007/s00423-009-0565-x. Epub 2009 Nov 19.
Tanrıkulu CÅž, Karamercan MA, Tanrıkulu Y, Öztürk M, YüzbaşıoÄŸlu Y, CoÅŸkun F. The predictive value of Alvarado score, inflammatory parameters and ultrasound imaging in the diagnosis of acute appendicitis. Ulus Cerrahi Derg. 2015 Jun 1;32(2):115-21. doi: 10.5152/UCD.2015.3103.
Dal F, Cicek Y, Pekmezci S, Kocazeybek B, Tokman HB, Konukoglu D, ÅžimÅŸek O, Taner Z, Sirekbasan S, UludaÄŸ SS. Role of Alvarado score and biological indicators of C-reactive protein, procalicitonin and neopterin in diagnosis of acute appendicitis. Ulus Travma Acil Cerrahi Derg. 2019 May;25(3):229-237. English. doi: 10.5505/tjtes.2018.57362.
Bal A, Anil M, Nartürk M, Özdemir T, Arikan A, KöylüoÄŸlu G, Polat B, ErdoÄŸan N, Bayol U, Özgüzer A, Çolak A. Importance of Clinical Decision Making by Experienced Pediatric Surgeons When Children Are Suspected of Having Acute Appendicitis: The Reality in a High-Volume Pediatric Emergency Department. Pediatr Emerg Care. 2017 Sep;33(9):e38-e42. doi: 10.1097/PEC.0000000000000763.
Naqvi SA, Thompson GC, Joffe AR, Blackwood J, Martin DA, Brindle M, Barkema HW, Jenne CN. Cytokines and Chemokines in Pediatric Appendicitis: A Multiplex Analysis of Inflammatory Protein Mediators. Mediators Inflamm. 2019 Feb 21;2019:2359681. doi: 10.1155/2019/2359681.
Moosmann J, Krusemark A, Dittrich S, Ammer T, Rauh M, Woelfle J, Metzler M, Zierk J. Age- and sex-specific pediatric reference intervals for neutrophil-to-lymphocyte ratio, lymphocyte-to-monocyte ratio, and platelet-to-lymphocyte ratio. Int J Lab Hematol. 2022 Apr;44(2):296-301. doi: 10.1111/ijlh.13768. Epub 2021 Nov 23.
Akgül F, Er A, Ulusoy E, ÇaÄŸlar A, Çitlenbik H, KeskinoÄŸlu P, ÅžiÅŸman AR, KarakuÅŸ OZ, Özer E, Duman M, Yılmaz D. Integration of Physical Examination, Old and New Biomarkers, and Ultrasonography by Using Neural Networks for Pediatric Appendicitis. Pediatr Emerg Care. 2021 Dec 1;37(12):e1075-e1081. doi: 10.1097/PEC.0000000000001904.
Kwan KY, Nager AL. Diagnosing pediatric appendicitis: usefulness of laboratory markers. Am J Emerg Med. 2010 Nov;28(9):1009-15. doi: 10.1016/j.ajem.2009.06.004. Epub 2010 Mar 9.
Zhang Y, Deng Q, Zhu H, Chen B, Qiu L, Guo C. Intermediate-term evaluation of interval appendectomy in the pediatric population. Eur J Trauma Emerg Surg. 2021 Aug;47(4):1041-1047. doi: 10.1007/s00068-019-01277-0. Epub 2019 Dec 10.
Benito J, Acedo Y, Medrano L, Barcena E, Garay RP, Arri EA. Usefulness of new and traditional serum biomarkers in children with suspected appendicitis. Am J Emerg Med. 2016 May;34(5):871-6. doi: 10.1016/j.ajem.2016.02.011. Epub 2016 Feb 12.
Slieker JC, Aellen S, Eggimann P, Guarnero V, Schäfer M, Demartines N. Procalcitonin-Guided Antibiotics after Surgery for Peritonitis: A Randomized Controlled Study. Gastroenterol Res Pract. 2017;2017:3457614. doi: 10.1155/2017/3457614. Epub 2017 May 16.
Liu Q, Xu K. Evaluation of some cellular biomarker proteins, oxidative stress and clinical indices as results of laparoscopic appendectomy for perforated appendicitis in children. Cell Mol Biol (Noisy-le-grand). 2020 Jun 5;66(3):197-203.
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